Genetics

Retinoblastoma

  • Tumour of primitive photoreceptor cells
  • Commonest ocular malignancy of childhood: 1 in 20,000
  • M=F
  • 40% are inherited: tumours tend to be bilateral and multicentric
  • Unilateral tumour is nearly always sporadic
  • Hereditary cases: only 10% have a positive family history. The…
Previous
Fluorescent In Situ Hybridisation (FISH)