Pathology

Collagen

  • Most common protein in animals
    • Extracellular framework for all multicellular organisms
  • Produced by fibroblasts
  • Basic unit is three polypeptide chains in a left-handed helix: regular triple helix (procollagen also contains a triple helix)
    • 2 alpha-1 chains
    • 1 alpha-2 chain
  • Types…
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