Pharmacology

Drug Vehicles

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  • Solutions: cause less blurring of vision than ointments
    • Ingredients can be added to increase viscosity (see above)
  • Semisolids/ointments: increased duration of action because of reduced dilution/clearance and prolonged corneal contact

    • Blur vision and can cause contact dermatitis
  • Slow-release preparations
    • Ocular inserts: eg. used for dry eyes
    • Collagen shields
    • Soft contact lens
    • Intravitreal inserts:
      • Ozurdex: dexamethasone intravitreal implant
      • Retisert: intravitreal pellets containing the steroid fluocinolone
      • Iluvien: intravitreal insert also containing fluocinoline

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