Uveitis
Voyt-Koyanagi-Harada syndrome
- Multisystem inflammatory disease affecting eyes, ears, brain, skin and hair
- T cell mediated autoimmune disorder against melanocyte antigens
- Higher prevalence in darker skinned races
- F>M
- 3rd and 4th decades
- Associated with HLA-DR4, especially HLA-DRB1*0405 (associated with melanocyte proteins)