Spirochaetal uveitis (including Syphilis)

Syphilis

• Treponema pallidum
• Transmitted sexually or transplacentally (congenital)
• Acquired vs Congenital

Primary (2-6 weeks from infection)

• Painless ulcer (chancre) with regional lymphadenopathy

Secondary (from 8 weeks)

• Maculopapular rash including palms/soles
• Generalised lymphadenopathy, malaise, fever
• Anterior/posterior uveitis: granulomatous or not, multifocal…