Melanoma

Benign features

• Absence of mitotic activity
• No intradermal migration
• No nuclear enlargement or pleomorphism
• Melanin in superficial layers but not deep layers

Conjunctival melanoma

• Premalignant lesions:

  • Primary acquired melanosis with atypia (75% of melanomas): conjunctival intraepithelial melanocytic neoplasia

    • Diffuse flat…